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Solution Reconstitution Calculator

Solute=Desired %Stock %×Q\text{Solute} = \frac{\text{Desired \%}}{\text{Stock \%}} \times QSolute=Stock %Desired %​×Q
Solute volume equals desired strength percentage divided by stock strength percentage times desired quantity

Solution

500 mL solute + 500 mL solvent
Solute (mL)
500
Solvent (mL)
500
Total (mL)
1000
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Understanding Solution Reconstitution

Solution reconstitution involves diluting a concentrated stock solution to a desired strength. This is commonly needed for enteral feedings, oral solutions, topical preparations, and irrigating solutions in nursing practice.

The calculator determines how much of the stock (concentrated) solution and how much diluent (usually sterile water or normal saline) to mix to achieve the desired concentration and volume.

Calculate Solution Reconstitution ↑

Worked Example

Prepare 1,000 mL of a 25% solution from a 50% stock solution.

Solute = (25 / 50) × 1000 = 500 mL of stock solution
Solvent = 1000 - 500 = 500 mL of diluent

Frequently Asked Questions

What is the difference between solute and solvent?

The solute is the substance being dissolved (the concentrated stock solution). The solvent is the liquid used to dilute it (such as sterile water or normal saline). Together they make up the final desired solution.

Can the desired strength exceed the stock strength?

No. You cannot make a solution stronger than the stock solution by dilution alone. The desired strength percentage must be equal to or less than the stock strength. If a higher concentration is needed, a different stock solution must be used.

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  • IV Flow Rate Calculator — Calculate IV drip rate in gtt/min and mL/hr.

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Disclaimer: This calculator is intended for educational purposes and to assist with solution preparation calculations. All results should be independently verified by a qualified healthcare professional. Always follow your facility's policies.